left sided pleural effusion case presentation (log 3)

Hello everyone, I am Aditya Rayilla, a medical intern and recently started my medicine posting. This blog is to share my medicine experiences and cases i come across during this period.




PRESENT CHIEF COMPLAINTS:
Patient has come due to lack of resolution of persistent cough, sob and now complains of Lack of appetite

Case History 
Bilateral pedal edema since 2 years intermittent pitting type ,pain less,gradually progressive below knee relieved on tablets 
Bilateral joint pain in the knee since 2years on NSAID abuse 
Decreased urine output associated with burning micturition since 2months 
associated with dribbling of urine , increased frequency hesitancy ,urgency , incomplete evacuation
SOB since 4 days grade 3-4 gradual in onset progresive
Orthopnea+ PND+ palpitations negative 
Chest pain since 4 days left sided heaviness ,not radiating 
Loss of appetite +
No h/o fever , cough 
No h/o HTN,DM,CVA,CAD,TB, EPILEPSY
no surgical history
Agricultural labourer by occupation stopped since 1 year
Alcohol occasionally 
 beedi smoker ( 1 beedi/ day)stopped 5 years back


General examination: (Present)
Pallor present 
Icterus absent 
No cyanosis clubbing lymphademopathy 
Edema of feet present B/L pitting type upto knee.
Dehydration present 
Temp Afebrile
Bp 130/80mm hg (present) supine position 
Pr 82 bpm (present)
Cvs s1 s2 hears no murmurs
Rs vesicular decreased on left ISA,no adventitious sounds
P/a soft non tender 
Cns Hmf intact
Speech normal 
No meningial signs 
cranial nerves ,motor system,sensory system,intact 
Reflexes present 
No cerebellar signs 

Treatment : (treatment on previous admission)
 1) tab. Lasix 40 mg / IV/ bd if sbp            >110 mmhg                                              2) tab pan 40 mg OD 
3)tab.pcm 650 mg sos
4) inj.neomol 1gm /IV/if temp >101F 
5)Monitor BP , pulse , temp .
6)temp charting 4th hourly &tepid sponging 
7)inj.augmentin 1.2gm/IV/bd
8)strict I/O charting

PRESENT TREATMENT
1.Inj. optineuron
2.Tab. pan 40mg/O.D
3.T. Lasix 20mg/iv/bd
4.T. Ultracet 1/2 tab QID
5.  Fluid restriction <1.5L/day
6. Strict I.V charting
INVESTIGATIONS (OLD)
19th may 202O
RBS 124 mg /dl 
Serum protein 6.2 g/DL
Serum LDH 449 IU/L
RFT  
       Urea : 61 mg /dl 
       Creatinine: 2.5 mg / dl                                            uric Acid 8.4 mg /dl 
       Calcium 10.5 mg / dl 
       Phosphorus 3.1mg / dl 
       Sodium. 140 meq / lit 
       Potassium 4.2 meq/ lit 
        Chloride 103 meq/ lit 
       
Pleural fluid 
       Protein : 4.2 gm / dl 
       Sugar :53 mg / dl
       LDH 807 IU/L  
CUE :
      Albumin :++
     3-4 pus cells 
     2-3 epithelial cells    
     RBC nill
     Sugars  nill
HEMOGRAM :
     Hb: 11.6 g/dl 
     WBC:13,300 cells / cumm
     RBC : 4.27 million/ cumm
     platelets: 3.74lacks/cumm 
     Lymphocytes 16%
     Smear : normocytic normochromic   
ABG :
pH 7.45
Pco2 23.8
Po2 74.8
Hco3 16.4
St.hco319.7
O2sat 95.7
Theraupetic pleural tap was done of about 500ml and the report showed exudative fluid

PATIENT HAS RE-VISITED US DUE TO PERSISTENT COUGH,SOB, LOSS OF APPETITE. Chest X-ray was done which didnt show any progression nor any resolution of the left sided pleural effusion.

NEW INVESTIGATIONS 
Pleural fluid (4/06/20)
                Sugar 74
                 Protein6.2
                LDH 476
Serum 
             protein 7.0
            LDH 263
Pleural Fluid

CELL COUNT PLEURAL FLUID

VOIUME 3 ML



COLOUR Pale yellow
APPEARANCEHazy ( clot)
TOTAL COUNT1900 Cells/cumm
DIFFERENTIAL COUNT
NEUTROPHILS 02
LYMPHOCYTES 98
RBC Nil
OTHERS Nil

ON CT SCAN (CT CHEST)
 * Centrilobular nodules with tree in bud appearance in apico posterior segment of left
upper lobe, superior segment & basal segment left lower lobe- Endobronchial infection.
* Loculated left pleural effusion with mild pleural thickening Chronic infection /
Empyema
* Generalized increased in bone density.
* Small right kidney; consistent with chronic kidney disease

Diagnosis:CKD stage 3b with secondary to NSAID abuse with moderate left sided pleural effusion (exudative)?. TB. ? malignancy ?. 


CASE SUMMARY
Here is an interesting case of a left sided pleural effusion of the lung, with CKD stage 3. The sob and cough had subsided to an extent and he got discharged but he came back due to a comparative increase in the cough and SOB. On X-ray Chest, the pleural effusion remained consistent on the left side. It neither appeared to  increase nor did it decrease. On pleural tap the fluid was again found exudative similar to the previous pleural tap fluid. On CT- chest, the radiologist report suggested that there was no mass most probably, but however we didn't rule it out completely and is yet to be evaluated, it showed signs of pleural thickening and infection. The CBNAAT result is still awaited and we have been under the thought that it'll most probably be tuberculosis rather than a malignancy and is yet to be evaluated. If malignant mass is suspected an FNAC Study has been suggested and ATT is to be started if malignancy is ruled out. Thanks to our colleague Dr. Vaishnavi for creating the previous log, we could access the patients previous data and could look at his previous case history.
               
   

Follow Up to be done after the CBNAAT of the pleural fluid result is obtained.

THANK YOU.

https://drive.google.com/folderview?id=1-3CcXEfPGnTUUTQvSDIuO3CXyckExJAa

Here is the link to the investigations, X-ray, CT- chest. 

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